The flight from Vancouver (YVR) to São Paulo (GRU) takes about 12h 21m nonstop on a widebody airliner, covering 6,867 miles (11,052 km).
São Paulo is 4 hours ahead of Vancouver. You cross 4 time zones heading east. Eastbound trips like this one tend to be harder to adjust to, so plan for a day or two of jet lag.
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